Science of Success



Identification of potent inhibitors of SARS-CoV-2 infection by combined pharmacological evaluation and cellular network prioritization

BY J.J. Patten, Patrick T. Keiser, Deisy Morselli-Gysi, Giulia Menichetti, Hiroyuki Mori, Callie J. Donahue, Xiao Gan, Italo do Valle, Kathleen Geoghegan-Barek, Manu Anantpadma, RuthMabel Boytz, Jacob L. Berrigan, Sarah H. Stubbs, Tess Ayazika, Colin O’Leary, Sallieu Jalloh, Florence Wagner, Seyoum Ayehunie, Stephen J. Elledge, Deborah Anderson, Joseph Loscalzo, Marinka Zitnik, Suryaram Gummuluru, Mark N. Namchuk, Albert-László Barabási and Robert A. Davey

Nutrient concentrations in food display universal behaviour

BY Giulia Menichetti and Albert-László Barabási

Quantifying NFT‑driven networks in crypto art

BY Kishore Vasan, Milán Janosov & Albert‑László Barabási

Recovery coupling in multilayer networks

BY Michael M. Danziger & Albert-László Barabási

Network medicine framework for identifying drug-repurposing opportunities for COVID-19

BY Deisy Morselli Gysi, Ítalo do Valle, Marinka Zitnik, Asher Ameli, Xiao Gan, Onur Varol, Susan Dina Ghiassian, J. J. Patten, Robert A. Davey, Joseph Loscalzo, and Albert-László Barabási

Network medicine framework shows that proximity of polyphenol targets and disease proteins predicts therapeutic effects of polyphenols

BY Italo F. do Valle, Harvey G. Roweth, Michael W. Malloy, Sofia Moco, Denis Barron, Elisabeth Battinelli, Joseph Loscalzo & Albert-László Barabási

A wealth of discovery built on the Human Genome Project — by the numbers

BY Alexander J. Gates, Deisy Morselli Gysi, Manolis Kellis & Albert-László Barabási




CCNR/The Lab: The Center for Complex Network Research (CCNR), directed by Professor Albert-László Barabási, has a simple objective: think networks. The center's research focuses on how networks emerge, what they look like, and how they evolve; and how networks impact on understanding of complex systems. To understand networks, CCNR's research has developed to rather unexpected areas. Certain studies include the topology of the www - showing that webpages are on average 19 clicks form each other; complex cellular network inside the cell-looking at both metabolic and genetic networks; the Internet's Achilles' Heel. The center's researchers have even ventured to study how actors are connected in Hollywood.