Barabasi Lab -- Center for Complex Network Research

• 1: H. Jeong, B. Tombor, R. Albert, Z. N. Oltvai, A.-L. Barabási
  The large-scale organization of metabolic networks
  Nature 407, 651–655 (2000) [ PDF ] Supplementary 1 , 2 , 3 ]
  
  

• 2: H. Jeong, S. P. Mason, A.-L. Barabási, Z. N. Oltvai
  Lethality and centrality in protein networks
  Nature 411, 41-42 (2001) [ PDF ] Supplementary 1 , 2 ]
  
  

• 3: J. Podani, Z. N. Oltvai, H. Jeong, B. Tombor, A.-L. Barabási, E. Szathmary
  Comparable system-level organization of Archea and Eucaryotes
  Nature Genetics 29, 54-56 (2001) [ PDF ] Supplementary 1 ]
  
  

• 4: E. Ravasz, A. L. Somera, D. A. Mongru, Z. N. Oltvai, A.-L. Barabási
  Hierarchical organization of modularity in metabolic networks
  Science 297, 1551-1555 (2002) [ PDF ] Supplementary 1 ]
  
  

• 5: R. J. Williams, N. D. Martinez, E. L. Berlow, J. A. Dunne, A.-L. Barabási
  Two degrees of separation in complex food webs
  Proceedings of the National Academy of Sciences 99, 12913-12916 (2002) [ PDF ]
  
  

• 6: Z. N. Oltvai, A.-L. Barabási
  Life’s complexity pyramid
  Science 298, 763-764 (2002) [ PDF ]
  
  

• 7: I. Farkas, H. Jeong, T. Vicsek, A.-L. Barabási, Z. N. Oltvai
  The topology of the transcription regulatory network in the yeast Saccharomyces cerevisiae
  Physica A 318, 601-612 (2003) [ PDF ] Supplementary 1 ] [ Fig(s). 1 , 2 , 3 , 4 ]
  
  

• 8: A.-L. Barabási
  Scale-Free Networks
  Scientific American 288, 50-59 (2003) [ PDF ]
  
  

• 9: G. Balazsi, K. A. Kay, A.-L. Barabási, Z. N. Oltvai
  Spurious spatial periodicity of co-expression in microarray data due to printing design
  Nucleic Acids Research 31, 4425-4433 (2003) [ PDF ]
  
  

• 10: H. Jeong, Z. N. Oltvai, A.-L. Barabási
  Prediction of protein essentiality based on genomic data
  ComPlexUs 1, 19-28 (2003) [ PDF ] Supplementary 1 ]
  
  

• 11: S. Y. Gerdes, M. D. Scholle, J. W. Campbell, G. Balazsi, E. Ravasz, M. D. Daugherty, A. L. Somera, N. C. Kyrpides, I. Anderson, M. S. Gelfand, A. Bhattacharya, V. Kapatral, M. D'Souza, M. V. Baev, Y. Grechkin, F. Mseeh, M. Y. Fonstein, R. Overbeek, A.-L. Barabási, Z. N. Oltvai, A. L. Osterman
  Experimental determination and system level analysis of essential genes in Escherichia coli MG1655
  Journal of Bacteriology 185, 5673-5684 (2003) [ PDF ] Supplementary 1 , 2 , 3 , 4 , 5 ]
  
  

• 12: S. Wuchty, Z. N. Oltvai, A.-L. Barabási
  Evolutionary conservation of motif constituents in the yeast protein interaction network
  Nature Genetics 35, 176-179 (2003) [ PDF ] Supplementary 1 , 2 ]
  
  

• 13: Z. Dezso, Z. N. Oltvai, A.-L. Barabási
  Bioinformatics analysis of experimentally determined protein complexes in the yeast Saccharomyces cerevisiae
  Genome Research 13, 2450-2454 (2003) [ PDF ] Supplementary 1 ]
  
  

• 14: M. A. de Menezes, A.-L. Barabási
  Fluctuations in network dynamics
  Physical Review Letters 92, 28701 (2004) [ PDF ]
  
  

• 15: R. Dobrin, Q. K. Beg, A.-L. Barabási
  Aggregation of topological motifs in the Escherichia coli transcriptional regulatory networks
  BMC Bioinformatics 5, 10 (2004) [ PDF ] Supplementary 1 ]
  
  

• 16: A.-L. Barabási, Z. N. Oltvai
  Network biology: understanding the cell’s functional organization
  Nature Reviews Genetics 5, 101-113 (2004) [ PDF ]
  
  

• 17: E. Almaas, B. Kovacs, T. Vicsek, Z.N. Oltvai, A.-L. Barabási
  Global organization of metabolic fluxes in the bacterium Escherichia coli
  Nature 427, 839-843 (2004) [ PDF ] Supplementary 1 ] [Cover]
  
  

• 18: S. Y. Yook, Z. N. Oltvai, A.-L. Barabási
  Functional and topological characterization of protein interaction networks
  Proteomics 4, 928-942 (2004) [ PDF ] Supplementary 1 ] [Cover]
  
  

• 19: G. Palla, I. Farkas, I. Derenyi, A.-L. Barabási, T. Vicsek
  Reverse engineering of linking preferences from network restructuring
  Physical Review E 70, 046115 (2004) [ PDF ]
  
  

• 20: A. Vazquez, R. Dobrin, D. Sergi, J.-P. Eckmann, Z. N. Oltvai, A.-L. Barabási
  The topological relationship between the large-scale attributes and local interactions patterns of complex networks
  Proceedings of the National Academy of Sciences 101, 17940-17945 (2004) [ PDF ] Supplementary 1 ] [ Fig(s). 1 , 2 , 3 , 4 , 5 ]
  
  

• 21: G. Balazsi, A.-L. Barabási, Z.N. Oltvai
  Topological units of environmental signal processing in the transcriptional regulatory network of Escherichia coli
  Proceedings of the National Academy of Sciences 102, 7841-7846 (2005) [ PDF ] Supplementary 1 , 2 , 3 ]
  
  

• 22: E. Almaas, Z.N. Oltvai, A.-L. Barabási
  The activity reaction core and plasticity of metabolic networks
  PLOS Computational Biology 1, 557-563 (2005) [ PDF ] Supplementary 1 ] [ Tables 1 ]
  
  

• 23: S. Wuchty, A.-L. Barabási, M.T. Ferdig
  Stable evolutionary signal in a Yeast protein interaction network
  BMC Evolutionary Biology 60, 8 (2006) [ PDF ] Supplementary 1 ]
  
  

• 24: J. Lim, T. Hao, C. Shaw, A.J. Patel, G. Szabo, J.F. Rual, C.J. Fisk, N. Li, A. Smolyar, D.E. Hill, A.-L. Barabási, M. Vidal, H.Y. Zoghbi
  A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration
  Cell 125, 801-814 (2006) [ PDF ]
  
  

• 25: J. Loscalzo, I. Kohane, A.-L. Barabási
  Human disease classification in the postgenomic era: A complex systems approach to human pathobiology
  Molecular Systems Biology 3 (124), 1-11 (2007) [ PDF ]
  
  

• 26: K.-I. Goh, M. E. Cusick, D. Valle, B. Childs, M. Vidal, A.-L. Barabási
  The human disease network
  Proceedings of the National Academy of Sciences 104 (21), 8685 (2007) [ PDF ] Supplementary 1 , 2 , 3 , 4 , 5 ] [ Fig(s). 1 , 2 , 3 , 4 ] [Website] [Poster]
  
  

• 27: D. Dupuy*, N. Bertin*, C. A. Hidalgo R.*, K. Venkatesan, D. Tu, D. Lee, J. Rosenberg, N. Svrzikapa, A. Blanc, A. Carnec, A. R. Carvunis, R. Pulak, J. Shingles, J. Reece-Hoyes, R. Hunt-Newbury, R. Viveiros, W. A. Mohler, M. Tasan, F. P. Roth, C. Le Peuch, I. A. Hope, R. Johnsen, D. G.
  Genome-scale analysis of in vivo spatiotemporal promoter activity in C. elegans
  Nature Biotechnology 25:6, 663-668 (2007) [ PDF ] [Cover]
  
  

• 28: V. Vermeirssen, M. Inmaculada Barrasa, C. Hidalgo, J.-A. B. Babon, R. Sequerra, L. Doucette-Stamm, A.-L. Barabási, A. J.M. Walhout
  Transcription factor modularity in a Gene-Centered C. elegans Protein-DNA interaction network
  Genome Research 17, 061-1071 (2007) [ PDF ] Supplementary 1 ]
  
  

• 29: A.L. Barabási
  Network Medicine — From Obesity to the “Diseasome”
  New England Journal of Medicine 357, 404-407 (2007) [ PDF ]
  
  

• 30: Q. K. Beg, A. Vazquez, J. Ernst, M. A. de Menezes, Z. Bar-Joseph, A.-L. Barabási, Z. N. Oltvai
  Intracellular crowding defines the mode and sequence of substrate uptake by Escherichia coli and constrains its metabolic activity
  Proceedings of the National Academy of Sciences 104, 31 (2007) [ PDF ] Supplementary 1 , 2 , 3 ]
  
  

• 31: M. A. Yildirim, K.-L. Goh, M.E. Cusick, A.-L. Barabási, M. Vidal
  Drug-target network
  Nature Biotechnology 25:10, 1119-1126 (2007) [ PDF ]
  
  

• 32: J. Park, A-L. Barabási
  Distribution of node characteristics in complex networks
  Proceedings of the National Academy of Sciences 104, 17916-17920 (2007) [ PDF ] [ Tables 1 , 2 ] [ Fig(s). 1 , 2 ]
  
  

• 33: A. Motter, N. Gulbahce, E. Almaas, A.-L. Barabási
  Predicting synthetic rescues in metabolic networks
  Molecular Systems Biology 4:168, 1-10 (2008) [ PDF ] Supplementary 1 ] [ Tables 1 , 2 , 3 , 4 ]
  
  

• 34: A. Vazquez, Q. K. Beg, M. A. de Menezes, J. Ernst, Z. Bar-Joseph, A.-L. Barabási, L. G. Boros, Z. N. Oltvai
  Impact of the solvent capacity constraint on E. coli metabolism
  BMC Systems Biology 2:7, 1-10 (2008) [ PDF ] Supplementary 1 ] [ Tables 1 , 2 , 3 , 4 , 5 ]
  
  

• 35: S. Lehmann, M. Schwartz, L. K. Hansen
  Biclique communities
  Physical Review E 78, 016108:1-9 (2008) [ PDF ]
  
  

• 36: D.-S. Lee, J. Park, K. A. Kay, N. A. Christakis, Z. N. Oltvai, A.-L. Barabási
  The implications of human metabolic network topology for disease comorbidity
  Proceedings of the National Academy of Sciences 105, 9880-9885 (2008) [ PDF ] Supplementary 1 , 2 , 3 ] [ Tables 1 , 2 , 3 , 4 , 5 ] [ Fig(s). 1 , 2 , 3 ] [Cover]
  
  

• 37: H. Yu, P. Braun, M. A. Yildirim, I. Lemmens, K. Venkatesan, J. Sahalie, T. Hirozane-Kishikawa, F. Gebreab, N. Li, N. Simonis, T. Hao, J.-F. Raul, A. Dricot, A. Vazquez, R. R. Murray, C. Simon, L. Tardivo, S. Tam, N. Svrzikapa, C. Fan, A.-S. de Semt, A. Motyl, M. E. Hudson, J. Park, X. Xin, M. E. Cusick, T. Moore, C. Boone, M. Snyder, F. P. Roth, A.-L. Barabási, J. Tavernier, D. E. Hill, M. Vidal
  High-Quality Binary Protein Interaction Map of the Yeast Interactome Network
  Science 322, 104-110 (2008) [ PDF ] Supplementary 1 ] [ Fig(s). 1 , 2 , 3 , 4 , 5 ]
  [ News & Views 1 ]
  

• 38: A. Vazquez, M. A. de Menezes, A.-L. Barabási, Z. N. Oltvai
  Impact of Limited Solvent Capacity on Metabolic Rate, Enzyme Activities, and Metabolite Concentrations of S.cerevisiae Glycolysis
  PLoS Computational Biology 4:10, 1-6 (2008) [ PDF ]
  
  

Barabási Lab / Center for Complex Network Research at Northeastern University * 111 DA/Physics Dept. * 360 Huntington Avenue * Boston, MA 02115